高原鼠兔低氧适应机制的研究概况

Adaptation Mechanism of Pika (Ochotona curzoniae) to Hypoxia

综述了新型实验动物———高原鼠兔对高原低氧环境的适应特点 ,并与移居大鼠、人类及世居高原人群的生理变化进行了比较 ,对于高原鼠兔的低氧适应机制 ,从血液学、氧的摄取、氧利用及肺循环的结构和功能 ,进行了较为系统的阐述 ,对高原适应的生理研究及发展方向也做了扼要介绍。

The adaptive characteristic of the new experiment animal, Pika (Ochotona curzoniae), to hypoxia was reviewed, and then compared with the physiological changes of the migrant rat, human being and the indigenous people on the plateau. The hypoxic adaptation mechanisms of Pika were systematically explored from hematology, oxygen intaking, ocygen utilization, structure and funcion of pulmonary circulation. Physiological properties and research trends have been briefly introduced in the plateau adaptation animal.