摘要
目的 :由同一高龋者口腔中分离出c血清型变形链球菌高致龋毒力的菌株和低致龋毒力的菌株 ,为变形链球菌的比较基因组研究奠定基础。方法 :从 4个方面比较 2 4株c血清型变形链球菌临床分离株对唾液包被羟基磷灰石的黏附能力、产酸和耐酸能力以及合成胞外多糖的能力。结果 :筛选出位于同一口腔中的高、低毒力株。结论 :同一口腔中存在着 2株或 2株以上致龋能力不同的c血清型变形链球菌。
AIM:To obtain high and low virulent strains of Streptococcus mutans serotype c from the same oral cavity of a high-caries subject and lay foundation for the comparative genomic study of Streptococcus mutans.METHODS:A total of twenty-four strains of Streptococcus mutans of clinical isolated serotype c were selected for investigation of virulence involved in the adherence to SHA, acidogenicity, acidodurance, and their ability to synthesize glucans. RESULTS:There were virulent and avirulent strains in the same oral cavity of a high-caries individual.CONCLUSION:More than one strains of Streptococcus mutans of serotype c existed with different cariogenic ability in the same oral cavity. [
出处
《牙体牙髓牙周病学杂志》
CAS
2003年第10期543-547,共5页
Chinese Journal of Conservative Dentistry
基金
国家自然科学基金资助项目 ( 3 0 2 714 17)
关键词
变形链球菌
毒力因子
致龋能力
Streptococcus mutans
virulent factor
cariogenic ability
