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MMPs与TIMPs在人脑胶质瘤侵袭性生长中的研究进展 被引量：2

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摘要 人脑胶质瘤是人类最为常见的恶性肿瘤之一,其突出的特点就是对人脑正常组织的侵袭性.目前认为在脑胶质瘤侵袭生长过程中,起关键作用的是一类基质金属蛋白酶( Matrix-metalloprot einase, MMPs).
作者 罗国才 叶应湖
机构地区 长江大学医学院外科教研室
出处 《卒中与神经疾病》 2003年第5期317-319,共3页 Stroke and Nervous Diseases
关键词 MMPS TIMPS 脑胶质瘤 侵袭性生长 研究进展 肿瘤抑制基因
分类号 R730.264 [医药卫生—肿瘤]
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参考文献17

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同被引文献23

  • 1何琳琳,王复新,王璇.大鼠脑出血周边组织MMP-2、MMP-9的动态表达及其与脑水肿关系的研究[J].黑龙江医药科学,2005,28(4):4-7. 被引量：4
  • 2Salaita k, Groves JT. Roles of the cytoskeleton in regulating EphA2 signals [J]. Commun Integr Biol, 2010, 3(5): 454-457.
  • 3Cheng N, Brantley DM, Liu H, et al. Blockade of EphA receptor tyrosine kinase activation inhibits vascular endothelial cell growth factor-induced angiogenesis [J]. Mol Cancer Res, 2002, 1 ( 1 ):2-11.
  • 4Kunishio K, Okada M, Matsumoto Y, et al. Matrix metalloproteinase-2 and -9 expression in astrocytic tumors [J]. Brain Tumor Pathol, 2003, 20(2):39-45.
  • 5Nakada M, Kita D, Futami K, et al. Roles of membrane type-1 matrix metalloproteinase and tissue inhibitor of metalloproteinases 2 in invasion and dissemination of hu- man malignant glioma[J].J Neurosurg,2001,94(3):464-473.
  • 6Sulman EP, Tang XX, Allen C, et al. ECK, a human EPH-related gene, maps to lp36.1, a common region of aheration in human cancers [J]. Genomics, 1997, 40 (2): 371-374.
  • 7Kataoka H, Igarashi H, Kanamori M, et al. Correlation of EphA2 overexpression with high microvessel count in human primary colorectal cancer[J]. Cancer Sci, 2004, 95(2): 136-141.
  • 8Holm R, de Putte GV, Suo Z, et al. Expressions of EphA2 and EphrinA-1 in early squamous cell cervical carcinomas and their relation to prognosis [J]. Int J Med Sci, 2008, 5 (3):121-126.
  • 9Lu C, Shahzad MM, Wang H, et al. EphA2 overexpression promotes ovarian cancer growth [J]. Cancer Biol Ther, 2008, 7(7):1098-1103.
  • 10Abraham S, Knapp DW, Cheng L, et ah Expression of EphA2 and Ephrin A-1 in carcinoma of the urinary bladder[J]. Clin Cancer Res, 2006, 12(2):353-360.

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卒中与神经疾病
2003年 第5期

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