血尿微量蛋白在高血压肾病早期诊断中的意义

Significance of Micro-protein in Blood Urine for Early Diagnosis of Hypertensive Kidney Disease

目的 分析血、尿微量蛋白在高血压肾病早期诊断中的意义。 方法 采用放射免疫分析方法 ,观察 4 0例原发性高血压病人血、尿系列微量蛋白的变化。 结果 显示常规尿蛋白 /肌酐 (β2 MG/Cr)、血α1-微球蛋白 /肌酐 (α1 MG/Cr)、β2 -微球蛋白 /肌酐 (β2 MG) ,高于正常 ,差异有显著性 (P <0 .0 0 5 )。 结论 血。

Objective The importance of micro-protein in blood urine in the early diagnosis of hypertensive kidney disease.Methods Using the method of radioactive and immune,we observed the changes of a series of blood and urine,and micro-proteins primary hypertension.Results The result showed that routine protein was negative,urin em ic ro-albumen/creatinine(ALB/α 1-microglobulins/creatinine(α 1-MG/Cr),β 2- microglobulins/creatinine(β 2-MG/Cr)and blood α 1-MG,β 2-MG was higher than normal.The difference was significant (P<0.005).Conclusion It showed that a series of micro-pro tein in blood and urine had certain value for diagnosing hypertens ion kidney disease.