以碱性成纤维细胞生长因子及其受体为靶点的黑素瘤治疗
摘要
碱性成纤维细胞生长因子的促增殖和促血管形成的功能在黑素瘤的发生、发展和转移中起重要作用。近来关于以成纤维细胞生长因子及其受体为靶点的黑素瘤治疗的研究逐渐增多,抗肿瘤生物治疗的特异性和靶向性已成为当前肿瘤治疗学中的研究热点。
出处
《国外医学(皮肤性病学分册)》
2003年第6期376-378,共3页
Foreign Medical Sciences(Section of Dermatology and Venereology)
参考文献25
-
1Widetitz RB, Jiang TX, Noveen A, et al. FGF induces new feather buds from developing avian skin J Invest Dermatol, 1996, 107(6) :797 - 803.
-
2Alanko T, Rosenberg M, Saksela O. FGF expression allows nevus cells to survive in three-dimensional collagen gel under conditions that induce apoptosis in normal human melanocytes. J Invest Dermatol,1999, 113(1):111-116.
-
3Vlodavsky I, Elkin M, Pappo O, et al. Mammalian heparanase as mediator of tumor metastasis and angiogenesis. Isr Med Assoc J, 2000, 2(Suppl) :37 - 45.
-
4Nesbit M, Nesbit HK, Bennett J, et al. Basic fibroblast growth factor induces a transformed phenotype in normal human melanocytes. Oncogene, 1999, 18(47) :6469 -6476.
-
5Coleman AB, lugo TG. Normal human melanocytes that express a bFGF transgone still require exogenous bFGF for growth in vitro. J Invest Dermatol, 1998, 110(5):793-799.
-
6Vacca A, Ria R, Ribatti D, et al. Angiogenesis and tumor progression in melanoma. Recenti Prog Med, 2000.91(11) :581 -587.
-
7Graeven U, Rodeck U, Karpinski S, et al. Modulation of angiogenesis and tumorigenicity of human melanocytic cells by vascular endothelial growth factor and basic fibroblast growth factor. Cancer Res,2001,61 (19) :7282 -7290.
-
8Berking C, Takemoto R, Satyamoorthy K, et al. Basic fibroblast growth factor and ultraviolet B transform melanocytes in human skin.Am J Pathol, 2001, 158(3) :943 -953.
-
9Xerri L, Battyani Z, Grob JJ, et al. Expression of FGFI and FGFR1 in human melanoma tissues. Melanoma Res, 1996,6 (3) :223 -230.
-
10Ahmed NU, Ueda M, ho A, et al. Expression of fibroblast growth factor receptors in naevus-cell naevus and malignant melanoma. Melanoma Res, 1997, 7(4) :299 -305.
-
1王楠,徐永华.佛波酯PMA促进碱性成纤维细胞生长因子(bFGF)释放及机理研究[J].实验生物学报,1998,31(1):41-48. 被引量:4
-
2李亚红,王黎明.碱性成纤维细胞生长因子及其受体与恶性血液病[J].西北国防医学杂志,2003,24(5):370-371.
-
3王志平,段国兰,陈一戎,秦大山,刘国栋,钮洪光.碱性成纤维细胞生长因子对膀胱癌细胞及膀胱癌患者LAK细胞的作用[J].中华泌尿外科杂志,1997,18(10):630-630.
-
4蔡欣然,黄长玉,殷凤峙.碱性成纤维细胞生长因子及其受体在肝胆管结石并发肝胆管癌中表达的意义[J].中华消化杂志,2000,20(2):99-101. 被引量:6
-
5刘争,安志强,李恩君,僧国珍.乙酰肝素酶、碱性成纤维细胞生长因子在胃癌中表达及对血管新生和肿瘤进展的影响[J].四川生理科学杂志,2004,26(3):106-108. 被引量:2
-
6杜建新,郭成浩.bFGF及其受体在乳腺癌新生血管中表达及定量分析的实验研究[J].中国临床医学,2004,11(2):182-183.
-
7程天明,袁爱力,李朝龙.一氧化氮与血管形成[J].国外医学(肿瘤学分册),1999,26(5):265-266. 被引量:7
-
8陈润琦,徐恩伟,李建民.VEGF-C VEGF-D对乳腺癌淋巴结转移的影响[J].山西医药杂志(上半月),2009,38(6):524-526. 被引量:1
-
9石岐兴,李芳,刘同才,张铭铮,孔垂泽.膀胱移行细胞癌中bFGF的表达及其与微血管定量的关系[J].临床肿瘤学杂志,2000,5(4):242-244.
-
10杜琳琳,卞修武,陈意生,史景泉,陈自强,柳凤轩.碱性成纤维细胞生长因子及其受体表达与胶质瘤恶性程度的关系[J].第三军医大学学报,2000,22(12):1121-1125. 被引量:2