血清降钙素原水平对泌尿系感染定位诊断价值的研究

The study of procalcitonin on differentiating acute pyelonephritis from lower urinary tract infection

目的:探讨降钙素原(PCT)对上、下尿路感染的诊断价值。方法:应用ROC曲线分析血清PCT的诊断价值,PCT测定采用免疫化学发光法。结果:急性肾盂肾炎患儿组PCT值明显高于下尿路感染组犤(3.90±3.51)ng/mlvs(0.48±0.39)ng/ml犦,且与肾受累程度相关。预测肾病变,PCT的敏感度为90.47%,特异度为88%。结论:PCT可用于鉴别上、下尿路感染,并与肾受累程度相关(P<0.01)。

Objective:To determine the diagnostic value of procalcitonin(PCT)in the differenti-ation between acute pyelonephritis(APN)and lower urinary tract infection(UTI).Methods:To evaluate the diagnostic effects of PCT by using the receiver operating characteristic (ROC)curve,Serum PCT as measured by immunolumino-metric assay.Results:The plasma levels of PCT in acute pyelonephritis patients were remarkably higher than those in lower UTI(3.90ng /ml ±3.51ng /ml vs.0.48ng /ml±0.39ng /ml).Moreover,the plasma levels of PCT were also correlated with the degree of severity of renal dam-age.For the prediction of renal lesions at admission,PCT had a sensitivity of90.47%and a specificity of88%.Conclusion:PCT values could be used to differentiate APN from lower UTI and to predict the degree of severity of renal lesions,P<0.01.