一种基于独立成份分析的fMRI时-空模型数据处理方法

A fMRI temporal -spatial model data processing using independent component analysis

独立成份分析(ICA)是信号处理领域中新近发展起来的一种很有应用前景的方法,而脑功能磁共振(fMRI)信号的有效分离与识别是一个正在研究和试验之中的技术领域。因此,发展基于ICA的fMRI数据处理方法具有明显的理论价值和应用前景。本文首先介绍了ICA原理,分析了现行ICA-fMRI方法采用的信号与噪声的空域分布相互独立的信号模型所存在的明显不足,然后提出了微域中的信号与噪声的时域过程相互独立的fMRI信号模型熏从而建立了一种新的fMRI数据处理方法:邻域独立成份相关法。合理的fMRI实验数据处理结果验证了新方法的合理性。

Independent component analysis (ICA) is a newly developed promising technique in signal processing applications. The effective separation and discrimination of functional magnetic resonance i-maging (fMRI) signals is an area of active research and widespread interest.Therefore-the development of an ICA based fMRI data processing method is of obvious value both theoretically and in potential applications. In this paper- introduced ICA principles and analyzed firstly is the drawback of the extant popular ICA-fMRI method where the adopted signal model assumes the independence of spatial distributions of the signals and noise. Then presented is a new fMRI signal model- which assumes the independence of temporal courses of signal and noise in a tiny spatial domain. Consequently we get a novel fMRI data processing method: Neighborhood independent component correlation algorithm. The effectiveness is elucidated through a real fMRI data test is presented.