期刊文献+

肿瘤基因表达谱的研究进展

Recent advances in tumor gene expression profiles
下载PDF
导出
摘要 基因表达谱的研究是近年来新的研究热点。通过对肿瘤基因表达谱的研究 ,深入了解肿瘤的发生机制 ,有助于找出肿瘤的早期诊断指标、治疗靶点、治疗应答和预后指标。现综述在基因转录和翻译两个层次上发展的基因表达谱的新技术 ,即核酸层次上的表达序列标签、基因表达系列分析和新近发展的cDNA微阵列技术 ,蛋白质层次上的二相凝胶电泳和测序质谱技术即蛋白质组技术 。
作者 顾小年
出处 《国外医学(肿瘤学分册)》 2003年第5期323-326,共4页 Foreign Medical Sciences (Cancer Section)
  • 相关文献

参考文献15

  • 1胡仁明,宋怀东,彭永德,彭永德,黄秋花,黄秋花,周隽,周隽,吴听彦,任双喜,王立,余亚萍,余亚萍,戴蒙,毛羽丰,徐淑华,徐淑华,范惠泳,沈宇,高国峰,汤正义,付刚,付刚,陈名道,张庆华,陈家伦.垂体瘤基因表达谱的建立及其发病分子机理的探讨[J].上海第二医科大学学报,2000,20(2):97-101. 被引量:7
  • 2Tan JM, Tock EP, Chow VT. The novel human MOSF-1(C8orf17) gene exhibits tissue specific expression, maps to chromosome 8q24.2 and is overexpressed/amplified in high grade cancers og the breast and prostate [J]. Mol Pathol, 2003, 56(2):109-115.
  • 3Stolf BS, Carvalho AF, Martins WK, et al. Differential expression of IGFBP-5 and two human ESTs in thyroid glands with goiter, adenoma and papillary or follicular carcinomas[ J ]. Cancer Lett, 2003,191(2) : 193-202.
  • 4Asmann YW, Kosari F, Wang K, et al. Identification of differentially expressed genes in normal and malignant prostate by electronic profiling of expressed sequence tags[J]. Cancer Res, 2002, 62(11) :3308-3314.
  • 5Xu LL, Su YP, Labiche R, et al. Quantitative expression profile of androgen-regulated genes in prostate cancer cells and identification of prostate-specific genes[J]. Int J Cancer, 2001, 92(3) : 322-328.
  • 6Waghray A, Schober M, Feroze F, et al. Identification of differentiaUy expressed genes by serial analysis of gene expression in human prostate cancer[J ]. Cancer Res, 2001, 61(10) : 4283-4286.
  • 7Liotta L, Petricoin E. Molecular profiling of human cancer[J]. Nat Rev Genet, 2000, 1(1): 48-56.
  • 8EI-Rifai W, Frierson HF Jr, Harper JC, et al. Expression profiling of gastric adenocarcinoma using cDNA array[J ]. Int J Cancer, 2001,92(6) : 832-838.
  • 9Moil M, Mimori K, Yoshikawa Y, et al. Analysis of the gene-expression profile regarding the progression of human gastric carcinoma [J]. Surgery, 2002, 131(1 Suppl): S39-47.
  • 10Hippo Y, Taniguchi H, Tsutsumi S, et al. Global gene expression analysis of gastric cancer by oligonucleotide microarrays[J]. Cancer Res, 2002, 62(1): 233-240.

二级参考文献25

共引文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部