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4-1BB与肿瘤特异性免疫治疗研究进展

4-1BB in tumor specific immunotherapy
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摘要 4 1BB(CD13 7)是新近发现的一种新型共刺激分子 ,其单独作用 (抗 4 1BBMoAb或 4 1BBL)及联用其他共刺激分子 (如B7 1)或细胞因子 (如IL 12 )显示了强效的抗肿瘤作用 ,且联用较单用时更显著、持久。现主要从 4 1BBL、抗 4 1BB MoAb及联用B7 1、IL 12等方面作一综述。
作者 马肖容
出处 《国外医学(肿瘤学分册)》 CAS 2003年第5期342-344,共3页 Foreign Medical Sciences (Cancer Section)
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