输血传播病毒标志物初复检模式在临床输血中意义的探讨

Investigate the Signification in Blood Test Quality to Re-Test of Standard Battery with Donation

目的:探讨献血者输血传播病毒标志物初复检模式在临床输血中的意义及作用。方法:回顾性研究自1994年至2001年间,对成品血液随机检测爱滋病(HIV)抗体,丙肝(HCV)抗体及乙肝表面抗原(HBsAg)测定,共12156份,按初复检前及初复检后两个不同规定检测标准时期进行分别统计。结果:开展初复检前阳性率HIV 0％;HCV 0.99％;HBsAg 0.70％;开展初复检后阳性率:HIV0％;HCV0.37％;HBsAg0.42;x^2:统计学有显著性差异(HCV:P<0.005;HBsAg:P<0.05)。结论:通过初复检,能很好地改善血液检测质量,但如要显著提高检测质量,应建立专门的试剂质量评估方法和提高试剂质量标准,并随科学技术的发展,将发展成熟的检测技术尽快用于实际检测。

Objective: To investigate important and action in clinical transfusion that re - test standard battery with donated blood. Methods: During 1994 to 2001, the donated blood were re - tested the HTV antibody, HCV antibody and HBsAg, total 12 156 samples, statistics that according the difference tests of standard battery.Results: Before retested, the percent of positive: HIV 0%;HCV0.99% ;HBsAg 0.70%; after retested, the percent of positive: HIV 0% ; HCV 0.37% ; HBsAgO.42; T?: (HCV: P <0.005; HBsAgrP < 0.05). Conclusion: To retest the standard battery can commendably ameliorate the quality of blood test, if markedness to advance the quality of blood test, it is important to advance the quality of reagent and upbuild a system to evaluate the quality of reagents, and to use the new method to test,example NAT method.