妊娠早期及中期筛查妊娠高血压综合征的进展

Progress in screening of pregnancy induced hypertension during the first and the second trimester pregnancies

妊娠高血压综合征是产科常见的并发症 ,对母婴危害极大 ,是孕产妇及围产儿死亡的重要原因之一。其临床症状由轻到重阶段发展 ,如能早期发现识别妊娠高血压综合征亚临床阶段 ,进行预防性治疗 ,可明显降低发病率。近年来许多学者致力于早期 (10～ 14孕周 )母体血清标记物的筛查及无创 2 4小时动态血压监测的研究。

Pregnancy induced hypertension(PIH) is a common obstetric complication, which is very dangerous to pregnant women and fetus, and it becomes one of important causes of deaths of pregnant women and perinatal neonates. The clinical symptom of PIH develops from slight to severe stages, therefore, morbidity of PIH can be reduced dramatically if sub clinical symptom can be examined and identified in the initial stage and preventive treatment is taken timely. Recently, many researchers have devoted themselves to the studies on screening of the markers in maternal serum during the early stage (at 10th～14th weeks) and noninvasive 24 hour pressure monitoring(ABPM). This article reviewed and summarized the progress in relating research on screening of PIH.