上海市1986～2001年梅毒实验室监测结果分析

Analysis of syphilis prevalence among STD ambulatory patients from 1986 to 2001 in Shanghai.

目的 分析上海市 1986～ 2 0 0 1年性病门诊病例和部分社会人群梅毒感染情况 ,探索梅毒流行规律 ,发现高危人群 ,为有关部门开展性病防治工作提供决策依据。方法 收集和整理上海市 1986～ 2 0 0 1年的性病门诊病例和部分高危人群的血清学检查结果 ,结合梅毒确诊试验进行统计学处理。结果 1986～ 2 0 0 1年共对 2 0 35 5人次做了梅毒确诊试验 ,包括梅毒暗视野检查、梅毒螺旋体血凝试验和荧光螺旋体抗体吸收试验 ,共发现梅毒阳性135 18人次 ,年均阳性检出率为 5 8 6 3%。其中男性检出率 5 1 5 3% ,女性检出率 70 6 5 % ,女性明显高于男性。从1995年起 ,上海市每年梅毒阳性检出数呈逐年快速上升趋势 ,并出现先天梅毒和小儿梅毒增多现象。结论 上海市性病门诊病例中 ,梅毒检出数和检出率逐年升高 。

objective To understand and analyze syphilis prevalence among STD ambulatory patients and some underground prostitutes and their clients from 1986 to 2001 in Shanghai and to provide decision makers with the scientific evidence to formulate the strategy of STD prevention and control.Methods The experimental data of the syphilis prevalence from 1986 to 2001 in Shanghai Dermatology Hospital were collected and analyzed.Results From 1986 to 2001,20 ,335 cases were tested with syphilis confirmation test by DFT, TPHA and FTA-ABS and 13,518 cases were found positive.The total positive rate of syphilis was 58.63% and the rate in female(70.65%) was higher than in male(51.53%).Since 1995,the number of syphilis cases have increased annually and congenital syphilis and infant's syphilis have emerged in Shanghai.Conclusions In the past 15 years,the number of syphilis cases and infection rate of syphilis increased significantly and the syphilis prevalence will continue to grow in the coming years unless effective measures are taken.