对美涤克灵免水消毒洁手液消毒功效的研究

Antimicrobial Efficacy of MediClean^(TM) Alcohol Gel as A Hand Sanitizer

目的 测试美涤克灵免水消毒洁手液 (6 0 %酒精凝胶 ,简称美涤克灵 )在医疗环境中的抗菌效果 ;评估美涤克灵在反复多次使用后的安全性。方法 对美涤克灵与普通洁手液和杀菌性洁手液的抗菌活性进行了比较 ;实验的设计和方法是遵照美国医护人员手部消毒标准步骤而完成的 ;手部皮肤对各种实验液体经 2 5次连续使用后的反应由皮肤病专家进行鉴定。结果 美涤克灵在标准的洗手过程中杀菌效果为最好 ,其次是杀菌性洁手液 ,再次是普通洁手液 ;美涤克灵和实验中使用的其他两种洁手液均未造成对手部皮肤的不良反应。结论 对于医护人员来说 ,无论是从杀菌效果、使用的便宜性或对手部皮肤的保护性来看 ,美涤克灵都是最理想的医用消毒洁手液 ;我们的实验结果显示美涤克灵也应是普通人群在居家、旅游、工作和上学等日常生活中的理想保健用品 ,因为该产品杀菌效果强、极宜使用 。

OBJECTIVE (1) To evaluate the antimicrobial effectiveness of MediClean TM Hand Sanitizer (a 60% alcohol gel) in a health care environment; (2) to assess the safety of MediClean to human hand skin after multiple repeated uses. METHODS The antimicrobial efficacy and irritation potential of 3 handwash product regimen was investigated: a nonantimicrobial lotion soap, an antimicrobial lotion soap, and MediClean. The regimens were evaluated by using a Healthcare Personnel Handwash procedure, and skin irritation was assessed by using expert hand evaluation after 22 consecutive washes. RESULTS The Healthcare Personnel Handwash data showed that the mean log reductions from baseline were greatest for the MediClean TM alcohol gel sanitizer, less for the antimicrobial lotion soap alone, and least for the nonantimicrobial soap. All of the product regimens showed a low potential for skin irritation. CONCLUSIONS In terms of both microorganism reduction and skin irritation, the most effective product regimen was the use of MediClean TM alcohol gel sanitizer. The usage of MediClean TM alcohol gel sanitizer can also be suggested to general public due to its easiness of use, effectiveness against microbes, and nonexistent skin irritation.