不稳定型心绞痛患者血C-反应蛋白 血沉和白细胞联合测定的意义

The Clinical Value of C-reactive Protein,ESR and WBC Determination in Patients with Unstable Angina Pectoris

目的 :探计炎症指标对不稳定型心绞痛 (UAP)的触发作用及对预后的影响。方法 :对 89例冠心病患者 (51例为不稳定型心绞痛 ,3 8例为稳定型心绞痛 )测定其C 反应蛋白 (CRP)、血沉 (ESR)及白细胞 (WBC)水平。CRP和ESR分别用免疫浊度法及魏氏法 ,WBC总数在CELL -DYN3 70 0血球计数仪上测定。结果 :UAP组患者CRP、ESR及WBC水平显著高于稳定型心绞痛 (SAP)组及正常对照组 ,SAP组患者的CRP水平显著高于对照组 ,而ESR、WBC水平与正常对照组无显著差异。结论 :高水平的CRP、ESR及WBC对不稳定型心绞痛的发生有关 。

Objective: To investigate the effects of inflam matory markers on pat hogenesis and prognosis of unstable angina. Methods: Assessed the levels of CRP,ESR and WBC in 89 patients with coronary artery disease (CAD) (51 with unstable angina pectoris and 38 with stable angina pectoris).CRP and ES R levels were deter mined with immune nephelometry and Westergren,WBC count were determined using CE LL-DYN 3700 Blood Ce ll. Results: The levels of CRP, ESR and WBC in UAP g roup were significantly higher t han SAP group and normal control group ( P <0.01).But there was no significant difference in the levels of ESR and WBC between SAP group and normal group ( P >0.05).Conclusion: The elevation of C RP,ESR and WBC is related with unstable angina pectoris and can predict it's pro gnosis.