摘要
玉米胚芽经提取精制得到粉状物(YF)。以含15％YF的饲料饲喂大、小鼠,可在短期内阻抑实验性高血脂大、小鼠血清总胆固醇(TC)的升高(P<0.01),并显著升高小鼠高密度脂蛋白胆固醇(HDL-C)含量(P<0.01),使TC-HDL-c/HDL-c显著降低(P<0.01)。对高血脂患者食用YF2个月的食疗观察表明,YF的降脂效果与动物实验一致,并且能使血浆卵磷脂酰基转移酶(LCAT)相对活性升高(P<0.05)。提示YF可能具有促进体内游离胆固醇(FC)转化为酯化胆固醇(EC),从而加速胆固醇从肝内移出的作用,对此尚需进一步研究。
The maize embryo was extracted and processed into pow aer nomed Yuqing Flour (YF) When mixed YF with the feed for experimental hyperlipeacia rats and mice.It resulted in decreased total serum cholesterol and in creased as compared with the control group, This result seemed to Suggest that YF in diet might effect the transformation of free cholesterol into the ester in liver.Further studies with increased number of patients are necessary to investigate the mechanism of the effect of YF on the lipid composition in lipemia.
基金
国家自然科学基金
