运动训练对大鼠白肌线粒体功能影响的研究

Influence of Exhaustive Exercise and Training on Fast Muscular Mitochondria in Rats

以大鼠力竭性运动为模型．观察了力竭运动和递增负荷训练对大鼠白肌线粒体脂质过氧化、抗氧化系统及总Ｃａ２＋浓度的影响。结果显示：力竭运动可使大鼠白肌线粒体脂质过氧化水平显著提高，线粒体超氧化物歧化酶（ＳＯＤ）的活性和线粒体还原型谷脱甘肽含量及总Ｃａ２＋浓度显著降低；而递增负荷训练可降低大鼠力竭运动后白肌线粒体脂质过氧化水平，提高大鼠力竭运动后白肌线粒体超氧化物歧化酶（ＳＯＤ）的活性，保持大鼠力竭运动后白肌线粒体还原型谷脓甘肽含量及总Ｃａ２＋浓度。

Taking incremental exercise to exhaustion, the authors measured MDA content SOD activity GSH Content and Total calcium concentration of the fast muscular mitochondria inrats at rest, im mediately after exhaustive haying trained during four weeks or not The resultsShowed that having trained decreased the lipid peroxidation level and increased SOD activities. GSH Content and total calcium concenh. ation significantly in the fast muscular mitochondria of rats after exhaustive exercise These findings suggested that having trained could decrease freeradicals, and thus protect the damage or fast muscular mitochondria from the lipid peroxidationafter exhaustive exercise and retain the function of the fast muscular mitochondria.