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健康人和感染患者抗绿脓杆菌内毒素蛋白(EP)抗体水平的测定分析

Assayand Analysis of Antibody Level of Anti-endotoxiN Protein of Pseudomonas Aeruginosa Between healthy Person and Patients
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摘要 用微量间接血凝法检测了健康人和绿脓杆菌感染患者血清抗EP抗体.健康人共检测154人.基础抗体水平绝大部分在1:8以下(占85.05%)EP—HA GMT为1:7.3.无性别差异(x^2=3.04、P>0.05).绿脓杆菌感染患者检测38例,免疫前GMT高于健康人1.43倍,免疫后较免疫前GMT提高4倍.绿脓杆菌EP是绿脓杆菌共同抗原,检查人抗EP抗体水平对诊断、防治绿脓杆菌感染具有重要临床意义. Antibody level of serum against Ep of healthy person and Patients infected Pseudomonas aeruginosa was analysed by a micro-passive hemag-glutination reaction in the artical Total healthy person 154 including 99 male and 55 female has been assayed Most part of basic antibody level is below 1:8 and 85.05% EP-HA GMT is 1:7.3 But it is not different between male and female (x2=3.04 P>0.05) a 37 Pseudomonas aeruginosa infected patients was assayed GMT is higher 1.43 fold (9.96/7.3) than healthy person before immunity and it is higher 4 fold (41.31/9.96) After immunity than before that The EP of pseadomonas aeruginosa is a common antigen of pseudomomas aeruginoa So to assay antibopy level of person serum against EP is very important for clinical diagnosis treatmant of infection of Pseudomonas aeruginosa.
出处 《生物技术》 CAS CSCD 1992年第1期37-39,共3页 Biotechnology
关键词 绿脓杆菌 内毒素蛋白 EP抗体 Pseudomonas aeruginosa Endotoxin protein EP Antibody Geometric Mean titer (GMT)
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