摘要
用光镜及组织化学方法观察结扎大鼠胆管1、2、3、4周后其肾脏的病理及组织化学改变,并以正常大鼠做对照,结果表明:胆道梗阻一周肾脏已出现病理改变,并随梗阻时间延长而加重;AKP、ATPase 活性减弱,而 ACP、LDH活性明显增强。
The kidneys of rats undergoing common bile duct ligation were studied with light microscope and histochemical method respectively at 1、2、3 ang 4 weeks postoperatively.The results revealed that:The kidneys had already taken on some pathologic changes at 1 w ek postope- ratively and then,the lesions gradually became serious with the time prolonged;Compared with control group,adenosine trip os atas (ATP ase)、alkaline phosphatase(AKP)activity decreased and low ver,acid phosphatase(ACP)、lactalic dehyrogenase(LDH)activity gradually intensified.