丹参注射液与黄芪注射液在5%葡萄糖注射液中的配伍稳定性观察

Observations on the stability of Salviae miltiorrhiza radix injection compatibilize with Astragalus injection in 5% glucose injection

目的 :研究丹参注射液与黄芪注射液在 5 %葡萄糖注射液中配伍的稳定性 ,为临床配伍使用提供依据。方法 :在不同温度 ( 10、2 5和 37o C)条件下 ,在 6小时内不同时间观察配伍液的外观、p H值、不溶性微粒的变化 ,并用紫外分光光度法观察配伍液的图谱变化 ,测定混合液中两种注射液主要成分的浓度。结果 :丹参注射液与黄芪注射液在 5 %葡萄糖注射液中配伍后 ,外观、p H值、不溶性微粒、紫外吸收图谱、主要成分含量基本不变。结论 :两种注射液可以在 5

Object: To study the stability of Salviae miltiorrhiza radix injection compatibilize with Astragalus injection in 5% glucose injection and provide a basis for cinical use. Methods: Under the conditions of different temperature (10, 25 and 37 oC, the appearance, pH and undissolved particles of compatible solution were observed within 6 hours. UV spetropotometer was used to observe the spectra changes and to determine the concentrations of main constituents of mix solution. Results: No change in appearance, pH, undissolved particles, UV absorbance spectra and concentrations of main constituents were observed in compatible solution. Conclusion: It's suitable for compatibility of two kinds of injections in the 5% glucose injection.