胰岛素基础—大剂量方案治疗青春期1型糖尿病儿童的疗效观察

Basic-large dosage insulin therapy in adolescence with type1diabetes mellitus:a preliminary observation

目的:观察胰岛素基础—大剂量注射方案治疗青春期1型糖尿病儿童的临床疗效。方法:采用胰岛素基础—大剂量治疗方案4次/d(睡前注射中效,三餐前注射短效)治疗4例青春期糖尿病患儿6月。结果:4例患儿慢性高血糖症得以控制,空腹及餐后血糖水平接近正常,糖化血红蛋白(HbA1c)基本恢复正常,酮症酸中毒发生减少。结论:胰岛素基础—大剂量方案治疗能够控制青春期糖尿病血糖水平。

Objective:To observe the effect of basic-large dosage insulin therapy on puberty patients with type1diabetes mellitus.Methods:Four puberty patients with type1diabetes mellitus were treated with basic-large dosage insulin therapy for a period of six months.Results:The hyperglycemia was gradually controlled,the fasting plasma glucose,the2h postprandial plasma glucose and HbA 1c levels were close to normal in four patients.The relapse of ketoacidosis decreased.Conclusion:The basic-large dosage insulin therapy can effectively control the glucose level of the puberty patients with type1diabetes mellitus.