蛛网膜下腔出血并发低钠血症的临床研究

The clinical research of hyponatremia following subarachnoid hemorrhage

目的 探讨蛛网膜下腔出血 (SAH)患者并发低钠血症的发生率、临床特点及发生机制。方法 分析 2 1例SAH并发低钠血症患者的临床、血清钠及CT资料。结果 SAH患者并发低钠血症的发生率占同期住院SAH患者的 3 2 .3 %,并发低钠血症者发生脑血管痉挛 (CVS)的发生率高于不伴低钠血症的SAH患者 (P <0 .0 5 ) ,低钠血症的发生与Fisher分级密切相关 ,前循环动脉瘤破裂所致的SAH患者更易发生低钠血症 (P <0 .0 5 )。

Objective To investigate the incidence, clinical characters and pathogenesis of hyponatremia following subarachnoid hemorrhage (SAH). Methods The clinical characters, serum natriumand CT data of 21 cases with hyponatremia following SAH were analysed. Results The incidence of hyponatermia following SAH was 32.3%, the incidence rate of cerebral vasospasm (CVS) in patients with hyponatremia was higher than that in patients without hyponatremia ( P <0.05). Hyponatremia correlated closely with Fisher grade, hyponatremia was easy to occur in patients with SAH caused by the rupture of aneurysm of anteror circulation ( P <0.05).Conclusion It should be vitals to improve the knowledge about the pathogenesis of hyponatremia following subarachnoid hemorrhage for theprevention and treatment of CVS rightly.