心血管危险因素对严重急性呼吸综合征分型及预后的影响

Effects of Cardiovascular Risk Factors on Patients with Severe Acute Respiratory Syndrome

为分析研究常见心血管危险因素对严重急性呼吸综合征(SARS)病人分型及预后的影响,对219例严重急性呼吸综合征病人进行分析,研究各年龄组及性别与SARS分型的关系,观察高血压、冠心病、糖尿病等基础疾病对此种疾病分型的影响,观察轻型、重型、极重型SARS病人的血糖、血脂、血压、血尿酸等指标的变化及其与SARS分型的关系。结果60岁以上老年人中重型及极重型病人的比例高于轻型组,且高于其他年龄组,而既往有高血压、糖尿病、冠心病等基础病者中重型及极重型病人明显多于无基础病变者。重型及极重型病人的血糖及收缩压水平明显高于轻型患者,极重型病人血尿酸水平低于轻型患者,而性别、血胆固醇、三酰甘油等指标与SARS分型无明显关系。提示年龄、高血压、高血糖等心血管危险因素对于SARS的分型及预后具有一定的影响,而性别、血胆固醇、三酰甘油水平对其分型无明显影响。

The objective was to investigate the effects of cardiovascular risk factors on different type of severe acute respiratory syndrome(SARS)and the patient's prognosis.Altogether219patients with severe acute respiratory syndrome were divided into three groups mild,severe and critically severe.The risk factors included age,gender,history of diabetes,hypertension,coronary artery disease,cerebrovascular disease and hypertriglyceridemia,elevated total cholesterol as well as high uric acid.These factors were estimated in different groups or types of patients with SARS.Results:More severe and critically severe cases were found in the groups of patients aged above sixty.In patients with history of hypertension,diabetes and coronary artery disease,severe and critically severe types were much more than other patients.In patients of severe and critically severe types,the level of blood glucose and systolic blood pressure were higher than patients with mild conditions.The level of uric acid in most severe patients was lower than mild patients.Gender,the level of total cholesterol and triglyceride didn't influence the conditions and prognosis of patients.Some cardiovascular risk factors such as age,hypertension and hyperglycosemia can affect patient's conditions and prognosis.Other risk factors such as gender,value of total cholesterol and triglyceride can't influence these significantly.