镇痛疗法预防顽固性拔齿后疼痛的临床研究

Clinical study of postoperative analgesia in dry socket

目的 探讨持续术后镇痛疗法预防干槽症 (DS)的临床意义。方法 选择 313例下颌阻生齿、下后牙死髓劈裂牙患者分为三组 ,A组 (术后镇痛组 )术后口服凯扶兰 2 5mg ,每 8小时 1次 (n =12 6 ) ;B组 (术后抗菌组 )术后口服克林霉素 ,0 .3g ,每日 3次 (n =10 0 ) ;C组 (对照组 )不用任何药物 (n =87)。观察凯扶兰、克林霉素对DS的预防效果。结果 重度疼痛率比较 ,A组明显低于B组和C组 ,差异显著 (P <0 .0 1) ;VAS评分比较 ,A组与B、C两组差异显著 (P <0 .0 1)。DS发生率比较 ,A组明显低于C组 ,差异显著 (P <0 .0 1)。结论 持续术后镇痛疗法可预防DS发生。其安全性和效果优于预防性应用抗生素。

Objective To study the clinical effect of postoperative analgesia in patients with dry socket (DS). Methods 313 cases with impacted teeth and complicated teeth of lower jaw were divided into three groups: A group (analgesia group) with NSAIDs analgesic kaflan tablets, 25mg,q8h(n=126);B group with clindamycin tablets, 0 3g,t.i.d(n=100);C group without any medicine(n=87).The destination was to observe the prevention of DS by kaflan and clindamycin. Result Group A was prominently different with group B and C in severe pain percentage?VAS mark and prevention of DS. Conclusion Continuous analgesia was helpful in prevention of DS. It was better than antibiotic in safety and therapy effect.