5Nelson LE, Lu J, Guo T,et al. The alpha2-adrenoeeptor agonist dexmedetomidine converges on an endogenous sleep-promoting pathway to exert its sedative effects[J]. Anesthesiolog'y,2003 ;98:428-36.
6Hsu YW,Cortinez LI, Robertson KM,et al. Dexmedetomidine pharmaeodynamics : part I : crossover comparison of the respiratory effects of dexme-detomidine and remifentanil in healthy volunteers [ J ]. Anesthesiology, 2004;101:1066-76.
7王伟朋,李立环.临床麻醉学[M].北京:人民卫生出版社,2004:1090.
8Ebert TJ, Hall JE, Barney JA, et al. The effects of increasing plasma concentrations of dexmedetomidine in humans[J]. Anesthesiology,2000;93 (2) :382-94.
9Paris A, Tonner PH. Dexmedetomidine in anesthesia. In :Paris A, ed. Curt Opin Anesthesiol [ M ]. Germang: Lippineott Williams & Wilkins, 2005 : 412-8.
10Gomez-Vazquez ME, Hemandez-Salazar E, Hemandez-Jimenez A, et al. Clinical analgesic efficacy and side effects of dexmedetomidine in the postoperative period after arthroscopic knee surgery [ J ]. J Clin Anesth, 2007 ;19:576-82.
