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莫西沙星的临床疗效及安全性 被引量:12

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摘要 莫西沙星(moxifloxacin)是一可口服的8-甲氧基喹诺酮类,1999年在美国批准上市,治疗敏感病原体引起的急性细菌性鼻窦炎、慢性支气管炎急性发作和社区获得性肺炎.本药结构特点为母环8位有甲氧基,7位上为二氮杂环取代. 这种新型喹诺酮药物除保持强大的抗革兰阴性菌活性外,对革兰阳性菌和其他非典型致病菌也具较强抗菌活性.对于卡他莫拉菌, 衣原体,脆弱拟杆菌, 葡萄球菌,链球菌,肠杆菌和厌氧菌的抗菌活性较环丙沙星和氧氟沙星强2~16倍.
作者 李性天
出处 《中国抗感染化疗杂志》 2001年第4期250-251,共2页 Chinese Journal of Infection and Chemotherapy
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