50株铜绿假单胞菌的耐药性分析

Analysis of resistance of fifty strains of pseudomonas aeruginosa to antibiotics

目的 评价铜绿假单胞菌对头孢吡肟和其它药物的耐药性。方法 应用ＳＣＥＰＴＯＲ系统和纸片法进行药敏测定。结果 ５０株铜绿假单胞菌的耐药率较高，对 １３种试验药物，耐药率 ４０％以上有 ８种，头孢西丁等 ３种达１００％，最低是亚胺培南为１４％，平均为５８．８％。结论 铜绿假单胞菌的耐药率较高，故主张联合用药。

Objective To evaluate the resistance of pseudomonas aeruginosa to cepfepime and other antibiot- ics . Methods SCEPTOR system and disk diffusion (K-B methods) were employed to determine the susceptibili- ty of pseudomonas aeruginosa to antibiotics. Results It showed that the resistance of pseudomonas aeruginosa to 13 antibiotics tested was high, the resistance rate to 8 antibiotics was over 40% and the resistance rate to cefoxition and other 2 antibiotics was as high as 100% ,with an average resistance rate of 58.8% (14%-100%). Conclu- sion The resistance of pseudomonas aeruginosa to antibiotics was relatively high and combined use of antibiotics was advocated.