麻疹疑似病例血清IgM抗体诊断结果分析

Analysis of the results of detection of IgM antibodies in the serum of suspected measles cases,

目的 为对麻疹疑似病例作出科学诊断。方法 采用酶联免疫吸附试验 (ELISA) ,对麻疹疑似病例的血清标本进行麻疹特异性IgM抗体检测。结果 1992年以来收集到的 187例麻疹疑似病例检测IgM抗体阳性率为 45 .5 % ,其中 2～ 6岁阳性率最高 ( 5 2 .6 % ) ,19例麻疹疑似病例进行风疹IgM抗体检测 ,结果风疹IgM抗体阳性率为 2 0 .1% ,说明麻疹疑似病例中有相当部分为风疹病例。阳性病例中无免疫史的占 2 1.2 %。结论 麻疹疑似病例不能单以临床症状进行诊断 ,应通过实验室检测IgM抗体才能准确诊断。进一步提高人群免疫水平是防止病例发生的最经济有效的措施。

Objective To diagnose scientifically suspected measles cases.Method ELISA was used to test all serum samples. Results 187 serum samples from suspected measles cases were tested. The positive rate of IgM of measles was 45.5%. Highest positive rate of 52.6% was observed in the age group of 2～6 years of 52.6% . 19 samples were tested IgM antibody of rubella. The positive rate was 20.1%. The result showed that some of suspected measles cases were actually rubella cases. 21.2% of positive cases had no immunization history of measles vaccine.Conclusion The suspected measles cases couldn't be diagnosed solely by clinic symptoms. The detection of IgM antibody is helpful to diagnosis. The enhancement of the immune levels of the population is the most economical and effective measure for the control of measles.