疣状胃炎的病因与治疗研究

A STUDY ON THE ETIOLOGY AND TREATMENT OF GASTRITIS VERRUCOSA

本文报告100例疣状胃炎的病因与治疗的研究结果,根据形态和病理特点将疣状胃炎分为急性期和慢性活动期。其中幽门弯曲菌(CP)阳性率分别为97％和68.7％,糜烂表面与周围非糜烂粘膜的CP阳性率分别为83.0％及45.％,加之CP数量与炎细胞浸润、胃粘膜糜烂程度与CP检出率均呈正相关,强烈提示疣状胃炎与CP感染密切相关。疣状胃炎的慢性活动期CP阳性的胃粘膜组织IgA、IgG,IgM检出率,血清IgA、IgG,胃液IgA,均高于急性期(P<0.05)。提示疣状胃炎与免疫因素(包括全身和局部)有关,尤其是在慢性活动期。用自制的“胃糜烂灵”治疗疣状胃炎疗效满意。

100 cases of gastritis verrucosa were classified into acute stage and chronic active stage according to the morpnological and histological characteristics.The CP positive rates in the above two stages were 97% and 68.7%,respectively,while that of the erosion area and the surrounding intact mucosa ' were 83.0% and 45.0%,respectively.The amount of CP was directly related to the degree of inflammatory cell infiltration and erosion.So VG was closely related to CP infection.In the chronic active stage,the detection rates of the Ig coated CP in the tissue section,serum IgA,IgG,and gastric juice IgA were all higher than those in the acute stage (P<0.05).This suggests that VG was related to immunological factors (systemic and local),particularly in the chronic active stage.The drug 'Wei-Mi-Lan-LingR' has a satisfactory therapeutic effect on VG.