摘要
研究了以磷酸三 (2 ,4-二氯 )苯酯为原料 ,经硝化、水解合成 2 ,4-二氯 -5-硝基苯酚的工艺 ,讨论了反应条件对反应的影响 ,获得了较好的工艺条件。在优化条件二步反应总收率为97% (以磷酸三 (2 ,4-二氯 )苯酯计 )。产物经IR及元素分析表征了结构。产品是合成多种高效除草剂如“稻思达”
The synthesis of 2,4-dichloro-5-nitrophenol(Ⅰ)from tri(2,4-dichlorophenyl)phosphate(Ⅱ)was studied.(Ⅱ)reacted with HNO 3 in the presence of conc. H 2SO 4 to formtri(2,4-dichloro-5-nitrophenyl)phosphate(Ⅲ).Then (Ⅰ)was produced by acidic hydrolysis of(Ⅲ).The total yield was 97% based on(Ⅱ). The effect of reaction time, catalyst and materials molar ratio etc. on yield of (Ⅰ).The structure of target compound was confirmed by IR and elementary analysis.
出处
《农药》
CAS
北大核心
2003年第11期21-22,共2页
Agrochemicals
基金
安徽省优秀青年科技基金项目资助 (No .3 1)
