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静脉滴注尼卡地平治疗老年人高血压危象的临床观察

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摘要 目的 观察尼卡地平对老年人高血压危象的疗效及安全性。方法 老年 (≥ 60岁 )高血压危象患者 92例 ,治疗前平均收缩压 (SBP)2 36± 1 6mm Hg和 /或舒张压 (DBP) 1 2 5± 1 1 mm Hg,以恒速输液泵持续静脉滴注尼卡地平 (佩尔地平 ) ,剂量为 0 .5~ 6μg/ kg/ min,根据血压每 5 min调整剂量 1次 ,每次增加 5μg/ min,直至达到目标血压 1 50~ 1 60 / 1 0 0~ 1 1 0 mm Hg,然后维持此血压水平 1~ 3d。结果 用药后 5min、1 0 min、30min、1 h、2 h的平均血压降至 2 31 / 1 2 5 mm Hg、2 2 6/ 1 2 3 mm Hg、2 1 7/ 1 2 1 mm Hg、2 0 7/ 1 1 8mm Hg、2 0 3/ 1 0 7mm Hg,2 4 h后达最大效应 ,血压平均为1 68± 1 1 / 1 0 0± 9mm Hg,并稳定至用药结束。未发现严重不良反应。结论 尼卡地平治疗老年人高血压危象起效快 ,降压作用平稳 ,安全性高。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2003年第11期742-743,共2页 Chinese Journal of Gerontology
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