检测C-反应蛋白在冠心病病变程度及预后价值的探讨

A discussion of the severity and prognosis inthe relationship between c-reactive protein and coronary heart disease of tested

目的 :探讨C -反应蛋白 (CRP)与冠心病 (CHD)病变程度及预后之间的关系。方法 :测定经临床确诊的CHD患者 1 38例的血清CRP浓度 ,并与非冠心病患者 5 9例的血清CRP浓度相比较。结果 :急性心肌梗死 (AMI)、不稳定型心绞痛 (UA)、稳定型心绞痛 (SA)及对照组其CRP血清浓度分别为 1 3.2 6± 1 .6 7mg/L、1 1 .2 3± 1 .0 8mg/L、8.1 7± 2 .0 1mg/L、4 .6 2± 1 .6 8mg/L、其中CHD单支变、双支病变及三支病变者其CRP浓度依次增高 ,分别为 8.5 4± 2 .0 3mg/L、1 0 .2 8± 1 .95mg/L、1 2 .1 9± 2 .37mg/L ,显示随着CRP浓度增高病变程度加重、发生急性冠状动脉事件也增高。结论 :检测血清CRP浓度对了解冠心病病变程度及预后有重要价值 。

Objective: A Disussion of the seveity and prognosis inthe reletionship between C-reactive protein(CRP) and coronary heart disease (CHD) .Methods: The plasma CRP concentrations were tested in 138 cases CHD and normal control group 59 cases .Results: Acute myocardia infarction (AMI), unstable angina pectoris (UA) ,stable angina pectoris(SA) and normal control group ,the plasma CRP concentrations was 13.26±1.67, 11.23±1.08, 8.17±2.01, 4.62±1.68 mg/L, respectively in the CHD group, the plasma concentrations were,8.54±2.03 ,10.28±1.95, 12.19±2.37 mg/L, respectively,for the 1-vessel-disease ,the 2-vessel-disease and the 3-disease,the indices of CRP concentrations higher was closely associated with pathological changes and acute coronary incident. Conclusion: The plasma CRP concentrations of tested to coronary heart disease of pathological changes severity and prognosis has important significance , one index for coronary heart diseases of detection.