肝脏纤维化指标的检测与分析

The test and analysis of liver fibroid indexes

目的 :通过对 1 5 6例肝病患者血清中四项肝纤维化指标—透明质酸、层粘蛋白、Ш型前胶原和Ⅳ型胶原的检测 ,来了解在肝炎病人向肝硬化转变的过程中 ,四项指标的变化情况。方法 :用放射免疫方法进行检测。结果 :在肝炎向肝硬化转变的过程中 ,每一个时期均可见到肝纤维化四项指标中的一项或几项的升高。结论 :肝纤维化指标与肝纤维化的进程密切相关 。

Objective: By testing the four liver fibroid index—Hyaluronic acid(HA),Laminin(LN), Procollagen typeⅢ(PCⅢ)and collogen type Ⅳ of 156 patient’s serum samples with liver disease, to explore their changes during the course from hepatitis to cirrhosis. Method: The radioimmunoassay(RIA) is used in the test. Result: During the change of hepatitis to cirrhosis, we can discover one or more of the four indexes rise in every phase. Conclusion: The liver fibroid indexes have very close relations to the progress of liver fibrosis. They have very important medical value in understanding the severity degree of patient’s liver fibrosis and cirrhosis.