对溴苄基溴的合成工艺研究

Synthesis of 4-bromo-1-bromomethyl-benzene

文章给出了对溴甲苯为原料直接溴化合成对溴苄基溴方法中的最适宜反应条件 :对溴甲苯与溴的投料比为 1∶0 95 ,反应温度为 98℃～ 10 2℃ ,后处理采用溶剂淋洗及混合溶剂重结晶的方法 ,得到的产品纯度大于 99% ,收率 6 0

The proper conditions are given in the process of 4 bromo 1 bromomethy1 benzene by brominating 4 bromo toluene with bromine:the rate of 4 bromo 1 bromomethy1 benzene and bromine is 1:0.95,the temperarure is 98℃～102℃.The crude product is washed and recrystallized by mixed solvent.Thus the purity is 99.3%,the yield is about 60%.