腹膜透析对尿毒症患者生活质量的影响

The Effect of Peritoneal Dialysis on Life Quality in End StageRenal Disease Patients

目的该文旨在观察规律性腹膜透析患者(2年左右)和刚开始腹透的尿毒症患者生活质量的不同,以比较腹膜透析对患者生活质量的影响。 方法78例腹透患者,规律性腹透(A组)45例,平均腹透龄24±16.6月;刚开始透析(B组)33例,平均腹透龄3.8±3.1月,用SF-36生活质量询问表进行评估。 结果A组患者的生活质量评分高于B组,尤其在躯体痛苦、情感问题所导致的角色限制和情感健康三项指标中差异显著(P均<0.05)。SF-36总分与腹透龄呈正相关(r=0.30,P=0.0039);两组营养状态无显著差异,透析均达充分性水平(P>0.05)。 结论随着腹透治疗的进行,患者生活质量逐步上升,从生活质量角度提示腹透是终末期患者的良好选择。

Objective The purpose of this study was to compare quality of life between long -term peritoneal dialysis ( PD) patients and new PD patients. Methods 78 patients were divided into long - term PD group ( group A, 45 ) and new PD group ( group B, 33 ). Average of PD duration in two groups were 24±16.6 months and 3. 8±3. Imonths. Quality of life was evaluated by the 36 -item short form health survey questionnaire (SF -36) , which contains eight domains. Adequacy (Kt/V, Ccr) and nutritional status (NPCR, sAlb, Hb) were also measured. Results According to SF -36, patients in group A had significantly higher scores in bodily pain, emotional well - being and role limitations caused by emotional problems, than those in group B (P all <0.05). The total SF -36 scores were positively correlated with PD duration. There are no differences between two groups in nutritional status. Adequacy of dialysis in both groups was reasonable. Conclusion Quality of life in PD patients will be getting better gradually with the time on PD. It is suggested that PD is a good choice for ESRD patients with respect to quality of life.