空间飞行对红曲霉菌产量的影响

Effect of Space Flight on Yield of Monascus Purpureus

目的选育高产洛伐他汀的红曲霉菌菌株。方法利用“神舟 3号”返回式飞船搭载了红曲霉菌。对搭载后的菌株进行复壮、分离和筛选 ,并进行固体发酵 ,检测发酵产物中洛伐他汀产量。结果从众多分离到的变异菌株中筛选到十几株高产洛伐他汀的菌株 ,一系列实验表明其高产性状是稳定的。

Objective To select high Lovastatin producing microbial breed by space flight. Method Monascus purpureus species was carried into space by the recoverable spaceship, “Shenzhou 3”. After flight, the strain was rejuvenized, segregated and selected. The content of Lovastatin produced in the solid fermentation was examined. Result Mutants with high productivity of Lovastatin were obtained. A series of tests showed that the acquired character of the mutants was stable. Conclusion Space flight is an effective method for the selection of fine strains.