壳聚糖与N-异丙基丙烯酰胺接枝共聚

Graft Copolymerization of N-Isopropylacrylamide with Chitosan

采用自由基溶液聚合 ,在水溶液中合成了具有温敏性的羧甲基壳聚糖接枝N 异丙基丙烯酰胺共聚物 ,采用红外、X射线衍射 ,对相关化合物进行了表征 ,并探讨了反应的机理。通过对温度、反应时间、引发剂浓度、溶剂体积、N 异丙基丙烯酰胺浓度的调节 ,获得最佳的反应条件 :壳聚糖 0 3g ,引发剂K2 S2 O810mg ,单体N 异丙基丙烯酰胺 1 5 g ,溶剂 (水 )用量 15mg ,70℃左右反应 2h左右。

The graft copolymerization of N-isopropylacrylamide(NIPA) onto chitosan has been investigated in water using K 2S 2O 8 as an initiator. The polymer products shows its property of thermosensitive and has been characterized by IR, XRD and TG. The effects of reaction time, temperature, amount of initiator, monomer and solvent had been studied, and the optimum condition was:Chitosan 0.3 g, K 2S 2O 8 10 mg, 70 ℃, NIPA 1.5 g, H 2O 15 mL, 2 h.