甲状腺功能亢进症患者的心率变异性分析

Analysis of Heart Rate Variability in the Patients with Hyperthy roidism

目的 :探讨甲状腺功能亢进症 (HT)患者的心率变异性 (HRV)。方法 :采用HRV分析中的 2 4h时域分析方法对HT患者 (82例 )和健康人 (72例 )的HRV进行对照。结果 :HT患者的SDNN、SDANNIndex、RMSSD和PNN50 四项指标均低于健康人 ,有统计学意义 (P <0 0 5～0 0 1)。而SDNNIndex则与健康人相近 ,无统计学意义 (P >0 0 5 )。结论 :HRV分析表明HT患者存在副交感神经活动 (张力 )的减弱和交感神经活动 (张力 )的增强 ,两者使交感 副交感神经系统动态平衡失调 ,最终表现为交感神经活动的相对亢进。

Objective:To investigate the heart rate variability (HRV)of the patients with hyperthyroidism(HT).Method :The 24 hour domain analysis in HRV was used to compare the patients(82 cases)of HT with health control(72 cases).Results:The SDNN, SDANN Index ,RMSSD and PNN 50 in HT group were significantly lower than in the control group(P<0 05～0 01),while the re was no significant difference in SDNN Index between two group(P >0 05).Conclusion:HT HRV analysis shows that imbalance of sympathetic p arasympathetic nerve system caused by decrease of parasympathetic activity and i ncrease of sympathetic activity in patients with HT shows finally relative excit ement of sympathetic activity.