急慢性肾衰的指甲肌酐测定与尿视黄醇结合蛋白检测的比较

THE VALUE OF COMPARING MENSTRUATING NAILCREATININE AND URINE RETINOL-BINDING PROTEIN IN CHRONIC RENAL FAILURE AND ACUTE RENAL FAILURE.

目的 :探讨指甲肌酐在鉴别急慢性肾衰的临床意义。方法 指甲肌酐 (NCr)应用碱性苦味酸法 ,尿视黄醇结合蛋白 (RBP)应用 EL ISA法及其与尿肌酐比值。结果 慢性肾衰组 (NCr)及健康对照组 (NCr)及急性肾衰组(NCr)比较有显著差异 (P<0 .0 1)健康对照组 (NCr)及急性肾衰组 (NCr)比较无显著差异 (P>0 .0 5 ) ,慢性肾衰组(RBP,RBP/Cr)及急性肾衰组 (RBP,RBP/Cr)与健康对照组 (RBP,RBP/Cr)比较有显著差异 (P<0 .0 1) ,慢性肾衰组 (RBP,RBP/Cr)与急性肾衰组 (RBP,RBP/Cr)比较无显著差异 (P>0 .0 5 )。结论 指甲肌酐含量的测定在鉴别急慢性肾衰中有着重要的临床价值。

Objective:To discuss the clinic significance about nail creatinine in patients of acute renal failure and chronic renal failure.Methods:To use the alkalescent picrate methodology menstruates the nail creatinine(NCr),and to use the ELISA methodology menstruates the retinol-binding protein(RBP),and to use routine methodology menstruates the proportionality between RBP and urine creatinine(RBP/Ucr).Results:In creatinine(NCr),there is a remarkable significance between chronic renal failure group and normal control group ,acute renal failure group(P<0.01),there is no significance between normal control group and acute renal failure(P>0.05),but in RBP,RBP/Ucr,there is a remarkable significance between significance,acute renal failure group and normal control group(P<0.01),there is no significance between in chronic renal failure group and acute renal failure group.Conclusions:There is significant value for differentiating chronic renal failure and acute renal failure.