念珠菌性龟头包皮炎的菌群分布与发病机理的研究

Study on distribution of fungal flora and pathogenesis of candidal balanoposthitis

目的 :探讨念珠菌性龟头包皮炎的菌群分布、抗生素应用与念珠菌感染的关系及条件致病菌的主要来源。方法 :采用菌种收集、鉴定 ,回顾以往的用药史。结果 :念珠菌性龟头包皮炎的致病菌以外籍菌为主 ;长期、大量使用抗生素是诱发菌群失调使外籍菌成为优势菌的主要因素 ;念珠菌性龟头包皮炎的菌群分布与女性念珠菌性阴道炎的菌群分布成正相关。结论 :预防念珠菌性龟头包皮炎发生的重点应以采取安全的性行为、合理使用抗生素以降低诱发因素为主要措施。

? Objective:To determine distribution of fungal florae of candial balanoposthitis (CBP),the relatioship between antibiotics administration and candial infection and the major source of opportunistic pathogens.Methods:The fungal strains were collected and identified,and the history of antibiotic administration was reviewed.Results:①Foreign fungi were predominant pathogens of CBP;②Dysbacteriosis induced by antibiotics stimulated the growth of foreign fungi,which resulted in CBP;③There was a positive relationship between fungal distribution of male patients and their sexual partners.Conclusion:In order to reduce the incidence of CBP safe coition and reasonalbe administration of antibiotics should be emphasized. 〔