忆立福治疗多发梗塞性痴呆40例临床分析

A clinical trial of YILIFU (aniracetam tablets) on 40 patients with multi-infarction dementia

目的 应用忆立福(阿尼西坦)对40例轻、中度多发梗塞性痴呆进行治疗,评价该药在治疗中的疗效和不良反应。方法 采用治疗前后临床疗效自身对照法。结果 治疗后HDS、MMSE、ADL、MQ均较治疗前有明显改善,治疗前后对比有显著性差异。结论 忆立福对多发梗塞性痴呆有较好的改善记忆障碍及提高日常生活能力的作用,且无明显副反应,安全性好。

Objective To evaluate the efficacy and safety of Yilifu on patients with multi - infarction dementia (MID) .Method The comparison of data between pre - and post - treatment was conducted. Results After treatment, the scores of HDS, MMSE and MQ were significantly increased (P < 0.001), with the score of ADL significantly decreased (P <0.001) .Mild adverse effects appeared in 20% of the patients.Conclusion Yilifu is an effective and safe drug which may significantly improve memory disorders and activity of daily life of patients with mild to moderate MID.