几种老年性疾病患者血液流变性及血脂变化

Changes of hemorheological Indexes and serum lipids of patients with elderly disorder

目的 :探讨脑梗死、高血压、冠心病、糖尿病等几种老年性疾病的血脂和血液流变学指标的变化。方法 :分别检测患者全血粘度 (ηb)、血浆粘度 (ηP)、红细胞压积 (HCT)、红细胞聚集指数 (EAI)、红细胞刚性指数 (TK)以及纤维蛋白原 (Fib)、胆固醇 (T ch)、甘油三脂 (TG)等指标 ,并与正常人对比分析。结果 :几种老年性疾病患者的血液流变学和血脂指标明显异常 ,与对照组比较差异有显著性 (P <0 .0 5～0 .0 1)。结论 :老年性疾病患者血液流变特性和血脂的异常改变 ,是引起体内血液瘀滞 ,导致微循环障碍和血栓形成的危险因素之一。检测这些指标 ,对老年性疾病诊断、治疗和预后判断具有重要意义。

Objective: To investigate the chenge of the hemorheological indexes and serum lipids(T ch, TG) in older patients with cerebral infarction, hypertension, coronary heart diseases and diabetes mellitus.Method: To detect ηb?ηP?HCT?EAI?TK?Fib?T ch?TG of the patients and 58 healthy people.Results: ηb?ηP?HCT?EAI?TK?Fib?T ch?TG were distinctly rised comparing with the control group( P <0.05～0.01).Conclusion: The abnormal changes of hemorheology and serum lipids of elderly disorder is one of the risk factors of blood block, capillary circulatory obstruction and thrombosis. Thus, the hemorheology and the lipids were examined maybe very important in diagnosis, treatment and prognosis of these diseases.