^(125)I籽粒治疗脑胶质瘤的研究进展

Advances in 125I seeds treating brain gliomas

脑胶质瘤占颅内肿瘤的近一半,因其大多呈浸润性生长,手术效果不佳,往往需要放疗辅助。间质内放疗自上世纪初出现以来,随医疗设备的不断革新而飞速发展。尤其20世纪80年代以后,125I籽粒以其对脑胶质瘤的良好疗效在国外得到大量应用,部分取代了常规外放射治疗,成为脑胶质瘤的重要治疗手段。本文对125I籽粒治疗脑胶质瘤的研究进展作一综述。

Glioma is the commonest intracranial tumor,and it accounts for almost half of intracranial tumors. Because the growth of most gliomas is invasive and operation results are not satisfactory,sometimes radiotherapies are necessary. Since the early years of last century, brachytherapy has been developing very fast along with inventions of new medical equipments. After 1980s,125I seeds have been widely used in many countries and partly replaced routine radiotherapies because of their good therapy results. 125I-seed-brachytherapy has already become an important treatment for brain gliomas. This article reviewed the present situation of brain gliomas treated by 125I seeds.