再生医学技术在烧伤传统治疗无效病人中的应用(附38例报告)

Application of regeneration medicine technology in treating burn patients not responded to conventional therapy(A report of 38 cases)

目的:总结重度烧伤传统疗法无效改为再生医学(MEBT/MEBO)技术治疗变化规律和临床经验。方法:将我科1995年5月至2002年5月收治的院外采用传统疗法无效改用MEBT/MEBO技术治疗的38例重度烧伤病人临床资料进行回顾性总结,病人一旦入院创面均改用MEBT/MEBO治疗,初始予以彻底清创,规范用药、规范操作,规范认识;全身实行系统综合治疗措施,以临床观察和病人感觉评价治疗效果。结果:本组38例全部治愈,未植皮自行愈合者21例,占55.26％,深Ⅲ度创面自愿要求植皮者17例,占44.74％。经随访多数无增生性瘢痕,部分愈后有局限性瘢痕,质软无残废。结论:重度烧伤经传统疗法久治不愈或疗效欠佳病人,病情复杂,并发症较多治疗难度也较大,再生医学可有效改善以上缺陷和病症,是重度烧伤病人传统治疗无效时的理想疗法。

objective: To sum up the experience with regeneration medicine (MEBT/MEBO) in treating severely burned patient not responded to conventional therapy. Method: 38 cases of severe burn not responded to conventional therapy were treated in our hospital using MEBT/MEBO. Firstly, all the wounds received thorough debriedement, then MEBO was applied according to standardized operation and dosage. Systemic and comprehensive measures were adopted and the efficacy was evaluated on the basis of clinical observation and patients' feeling. Result: All 38 patients were cured. 21 cases had not received skin grafting (55, 26% ). 12 cases of deep third degree burn received skin grafting at their own will (44. 74% ). After followed - up, most of the patients had no hyperplastic scar formation, a few of them had localized soft scar but no disablement. Conclusion: Severely burned patients not responded to conventional therapy always had complicated disease course and were difficult to cure. Regeneration medicine provided an ideal method for treating patients of the kind.