应用平均动能变化率评价肺动脉高压右心室收缩功能

To evaluate the right ventricular systolic function with the mean rate of kinetic energy change in pulmonary hypertension

目的 应用平均动能变化率 (dm/dt)评价肺动脉高压时右心室收缩功能。方法 通过对 2 0 0 0年 10月至2 0 0 1年 12月在我院住院的 10 5例左向右分流型先天性心脏病 (CHD)进行彩色多谱勒超声心动图测定平均动能变化率 (dm/dt)和心导管检查 ,探讨肺动脉高压 (PH)时dm/dt的特点 ,并与血液动力学参数对照 ,评价dm/dt与dp/dtmax相关性及dm/dt在不同PH时的特点。采用方差分析病例组及对照组的差异 ,P <0 .0 5为有统计学意义。结果 病例组与对照组相比 ,病例组的Dm/dt明显增加 (P <0 .0 0 1)。病例组亚组之间比较 ,无PH组dm/dt低于中、重PH组 (P<0 .0 5 )。重PH组dm/dt较中PH组dm/dt降低 (P <0 .0 5 )。dm/dt与dp/dtmax呈正相关 (r为 0 .85 ,P <0 .0 5 )。结论 dm/dt与dp/dtmax相关性好 ,可以较好地反应右心室的收缩功能。PH组dm/dt明显增高 ,严重肺高压时dm/dt仍较对照组高 ,但较轻、中PH时低。

Objective To evaluate the systolic function of right ventricule with mean rate of kinetic energy change (dm/dt) in pulmonary hypertension. Methods To mensurate the mean rate of kinetic energy change (dm/dt) ,and the systolic pressure in pulmonary artery(PASP)?the mean pressure in pulmonary artery(PAMP)through Doppler cardiograph and right cardiac catheterization in 105 cases of left to right shunt congenital heart disease between Oct 2000 and Oct 2001 , we dicuss the character of dm/dt in pulmonary hypertension. all quantitative data present as mean±standard deviation; all control data and contrast data were managed with analysis of variance; P<0.05 is significant.Results contrast to the contrast case, dm/dt in control case is higher obviously(P<0.001), and dm/dt in sever PH group is lower than in mild and moderate PH groups compared in subgroups of control case. the dm/dt is positive correlation with dp/dt?Qp (r equal 0.85?0.58 individually, P<0.05).Conclusions the dm/dt is positive correlation with dp/dt and present right ventricular systolic function perfectly. dm/dt is higher in control case, dm/dt in sever PH is lower than in mild and moderate PH and higher than contrast case.