摘要
目的 :探讨袁氏镇心痛对冠心病血小板功能的影响。方法 :选用Wistar大鼠 4 0只 ,随机分为 5组 ,以地塞米松腹腔内注射制成血瘀模型 ,分组同时给予不同剂量袁氏镇心痛及肠溶阿司匹林灌胃 ,8d后检测血浆GMP - 14 0含量。结果 :模型空白组血浆GMP - 14 0增高 ,治疗组血浆GMP - 14 0均较低。结论 :袁氏镇心痛能够抑制血小板活化。
Objective: To explore the effect of this medicine on the platelet function in coronary heart disease. Methods: Choose 40 Vistar rats, and divide them randomly into five groups, followed by intra-abdominal injection of Disaxymisone. Meanwhile raise the rats in the treatment group with this medicine and enteric aspirin, the GMP-140 tested eight days afterwards. Results: The GMP-140 in the blank group rose, while that in the treatment group was fairly low. Conclusion: This medicine can prevent platelet activation.
出处
《河南中医学院学报》
2003年第6期23-24,共2页
Journal of Henan University of Chinese Medicine
关键词
袁氏镇心痛
冠心病
血瘀症
血小板活化
大鼠
Yuan's Zhenxintong
coronary heart disease
blood stasis syndrome
platelet activation
rats
