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食管癌细胞凋亡水平与临床病理特征的关系 被引量:1

The relationship between apoptosis and clinical pathological features of esophageal carcinoma
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摘要 目的 探讨食管癌细胞凋亡与临床病理特征的关系。 方法 应用末端脱氧核糖核苷酸转移酶介导的d UTP缺口末端标记法 (TUNEL )检测 30例食管癌患者的食管癌细胞凋亡水平 ,并分析其与临床病理特征的关系。结果 有淋巴结转移患者的食管癌细胞凋亡指数 (AI)低于无淋巴结转移的患者 (P<0 .0 5 ) ,高分化食管癌患者 AI高于中 -低分化患者 (P<0 .0 1) ,食管癌 AI与患者的性别、年龄和肿瘤病理分期无明显关系 (P>0 .0 5 )。 结论 食管癌患者的细胞凋亡水平与其临床病理特征有密切关系。
出处 《中国胸心血管外科临床杂志》 CAS 2003年第4期319-320,共2页 Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
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同被引文献5

  • 1Vermeulen K, Berneman ZN, Van Bockstaele DR Cell cycle and apoptosis [ J ]. Cell Prolif, 2003, 36 (3) : 165 - 75.
  • 2Fernandez Y, Gu B, Martinez A , et al . Inhibition if apoptosis in human breast cancer cells:role on tumor progression to the metastatic state[ J]. Int J Cnacer ,2002,101 (4) :317 - 326 .
  • 3Shibakita M, Tachibana M, Dhar DK , et al. Spontaneous apoptosis in advanced esophageal carcinoma: its relation to Fas expression[J]. Clin Cancer Res, 2000, 6:4755-4759.
  • 4Reed JC. Mmeehanism of apoptosis[J]. Am J Path, 2000,157(5) :21415 - 1430.
  • 5彭心昭,黎妙娟,沈忠英,朴英杰.食管癌癌变过程中的细胞凋亡及其与细胞增殖的关系[J].第一军医大学学报,2000,20(1):55-58. 被引量:2

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