摘要
目的 探讨尿蛋白-1(UP-1)时糖尿病肾病的诊断价值。方法 用酶联免疫法测定90例2型糖尿病患者尿中UP-1、N-乙酰-β-D-氨基葡萄糖苷醇(NAG)、β_2-微球蛋白(β_2-MG)的含量。结果 糖尿病患者尿UP-1含量与对照组间差异有显著性意义(P<0.01),UP-1与尿Alb、尿NAG和β_2-MG呈正相关。结论UP-1可作为诊断早期糖尿病肾病的敏感指标。
Objective To study the diagnostic value of urine protein 1 ( UP - 1) in diabetic nephropathy. Methods
The concentration of UP - 1 in the urine of type 2 diabetes mellitus was measured by ELISA. The concentration of N - acetyl -
beta - D - glueosamindase (NAG) and beta2 - microglobulin ( β2 - MG) in the urine were also measured. Results There
were significant difference in UP - 1 amony all groups ( P <0. 01 ). UP - 1 related positively to urine Alb, urine NAG and β2
- MG. Conclusion UP - 1 is an indicator of the diagnosis of the early diabetic nephropathy.
出处
《中国全科医学》
CAS
CSCD
2003年第12期989-990,共2页
Chinese General Practice
