父母接触CS_2与子女智能发育的关系

Investigation of the Relationship between the Parents CS_2 Exposure and the IQ Development of Their Offspring

目的 研究父母怀孕前接触不同浓度CS2 对子女智商发育的影响。方法 应用WlSC -R对父母孕前接触CS2 >2a的 6 1名儿童和 39名对照组儿童进行智商测定 ,并计算平衡年龄、文化因素后的智商得分 (VIQ ,PIQ ,FIQ)和因子 (A ,B ,C因子 )得分。结果 不同浓度接触组与对照组比较 ,经单因素方差分析 ,智商和因子得分差异均有显著意义 ,其中高浓度组得分最低。将接触组儿童分成父亲接触组、母亲孕前接触组 ,并与对照组进行比较 ,3组智商和因子得分差异有非常显著意义 ,父亲接触组得分最低。经Dunnett分析表明 ,父亲接触组与母亲接触组及对照组比较 ,差异有显著性。母亲接触组与对照组比较 ,差异无显著性。相关分析表明 ,母亲和父亲文化水平、孕前工龄、生育年龄、新生儿出生体重与儿童智商得分有相关关系。多元逐步回归分析表明 ,只有父母亲文化水平、父亲接触工龄等进入回归方程。结论 父亲高浓度接触CS2 将导致子女智力发育水平低下 ,父亲接触CS2 其子女智商得分低于母亲孕前接触组 ,接触组儿童智力发育与父亲接触工龄有关 。

Objective To investigate the impacts of parents CS 2 exposure prior to pregnancy on intelligence quotient(IQ)development of their offspring.Methods Using the WISC R to measure IQ of 61 children whose parents had CS 2 exposed prior to pregnancy and 39 children whose parents without CS 2 exposure as the control.Scores of VIQ,PIQ,FIQ,and A,B,C factors were calculated after balancing age and education factors.Results The analysis by one way Anova showed that the differences in scores of IQ and factors among three exposed groups of fathers,mothers and the control were remarkably significant.The IQ scores in high concentration group were the lowest.Children of exposed group were divided into fathers exposed and mothers exposed ones,and compared with the control group.There was a notable significance in the difference of their IQ and factors scores.The fathers exposed ones got the lowest score.Dunnett analysis showed that there was no notable significance between the mothers exposed group and the control group.The results of correlative analysis showed that the education status,length of service before pregnancy,age of procreation,the body weight at birth all can affect on the scores of children IQ.The results of multiple liner regression analysis showed that only parent education status and the length of exposure of fathers were in the regress equation.Conclusions When fathers exposed to high concentration CS 2,it will induce low IQ development of their offspring,Offspring IQ of the fathers exposed group was lower than that of the mothers exposed group.IQ development of children in exposed group correlated with the lenght of exposure of fathers and their parent education status.