老年人散发急性肝炎病原学及临床分析

The Etiology and Clinical Features of Acute Sporadic Hepatitis in the Elderly

目的 为探讨老年人散发急性肝炎病原学构成及临床特点 ,为老年人病毒性肝炎的防治提供依据。方法 对近年住院治疗的散发急性老年肝炎患者 94例 ,用 EL ISA、PCR和 DOT进行血清学分型并对其临床资料作初步分析。结果 甲、乙、丙和戊型肝炎分别占 1 3.83%、3.1 9%、5 .32 %和 6 5 .95 % ,混合感染占1 7.0 2 %。 5型肝炎标志物阴性 1 3.83% ,其中药物性肝炎 5例 ,占 5 .3%。老年人急性肝炎的特点为黄疸深 ,住院时间长 ,单一感染者均顺利恢复 ,混合感染 1 6例中 3例因肝衰竭而死亡。结论 本地区 ,老年人甲、乙、丙和戊型肝炎均有散发 ,多为单一感染 ,少数为混合感染 ,可能存在新的肝炎致病因子。老年人药物性肝炎应受重视。

Objective To analyze the etiology and clinical features of acute sporadic hepatitis in the elderly and provide some ideas for its prevention and treatment.Methods Ninty four in patients' clinical information was collected and serum samples were taken for anti HAV,HBV Marker,anti HCV,and anti HEV by ELISA.Results The ratio of hepatitis A?B?C?E and co infected was respectively 13.83%,3.19%,5.32%,65.9% and 17%.The ratio of non A?B?C?E hepatitis was 13.7% respectively.There were 5 inpatiens suffered from hepatitis due to drug in take.Conclusion In this area,hepatitis A,B,C and E were sporadic in the elderly,most of them were singly infection.It is possible that there is new pathogenetic factor.Attention should be paid to drug hepatitis.Mixed infection might be one of the death causes in this population.