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THE CORRELATIONS OF CLINICOPATHOLOGIC FEATURES, HORMONE RECEPTOR LEVEL WITH THE PROGNOSIS OF BREAST CANCER: REPORT OF 308 CASES IN ELDERLY WOMEN

THE CORRELATIONS OF CLINICOPATHOLOGIC FEATURES, HORMONE RECEPTOR LEVEL WITH THE PROGNOSIS OF BREAST CANCER: REPORT OF 308 CASES IN ELDERLY WOMEN
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摘要 Objective. This study analyses the clincopathologic features and hormone receptor level of breast cancer in aged patients(≥60 years) and explores the related factors of the prognosis.Methnds. For all patients,the clinical data and pathologic data were reviewed retrospectively. Followup data were available. Of the 308 cases,tumor specimens in 130 patients were subjected to hormone receptor analysis by a dextran-coated charcoal technique.Results’ Of the 308 cases, 82 cases were in stage I, 147 cases in stage II, 66 cases in stage III,and 13 cases in stage IV. Metastatic rate (axillary lymph nedes) was 35. 7%. The overall postoperative 5 and 10-year survival rates were 70. 8 % and 50. 5 %,respectively. Estrogen receptor and progesterone receptor positive rates were 66. 9 % and 40.0%,respectively. The survival rate was decreased with the increasing grade of TNM(P<0.01). The mortality rate of the breast cancer was related to the clinical stage and the hormone receptor level (P<0. 05 ).Conclusbos. There was a relatively gdri prognosis in this series. The size of tumor, number of metastatic nedes and hormone receptor level were related to the prognosis.
出处 《Chinese Medical Sciences Journal》 CAS CSCD 1997年第1期60-62,共3页 中国医学科学杂志(英文版)
关键词 breast cancer ESTROGEN PROGESTERONE PROGNOSIS 相关性 病理特征 荷尔蒙受体 预后 乳肿癌
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